The FDA Changes the Warning Notices

Many people think the Food and Drug Administration's role is limited to licensing new drugs and medical devices,but it actually has a post-marketing role as well. Doctors and hospitals all round the US are required to report any and all adverse side effects to drugs.It's not uncommon to find that drugs can pass through clinical trials involving only thousands of participants, but show side effects when millions start taking them.Obviously, many problems come from those who abuse the drugs in one way or another but, every now and again,serious problems emerge over time. Once a pattern emerges,the FDA can either change the labels on the drugs to give stronger warning to patients or,in the worst cases,withdraw the licenses for the drug to be used. Since withdrawal can have a dramatic effect on the manufacturer, the FDA prefers to improve the level of warnings unless the problems are too severe to ignore.

Doctors have been aware of the problems of serotonin syndrome for some years. It's a potentially serious adverse side effect when people ingest too much serotonin. Perhaps it's better to think of this as a form of poisoning caused when people take excessive dosages of one drug or mix different drugs together. The effects fall into four main classes:

  • a change to metal status - you may become agitated, hallucinate or, in extreme cases, fall into a coma;
  • the body may start to function erratically and your blood pressure rises, your heart races and your body suddenly loses or retains heat;
  • loss of physical co-ordination; and/or
  • nausea, vomiting and diarrhea.
In some cases, the result has been death, e.g. the high-profile case of Libby Zion in 1984 which produced a change in the law of New York limiting the working hours for medical postgraduates and requiring their close supervision by senior physicians at all times. Thus, the FDA is not reacting to a new problem, but merely increasing the visibility of the warning notices as it affects all drugs containing serotonin.

In this instance, the warnings affect tramadol in the following ways. It always has been the case that an overdose of any of the opioid painkillers can cause this syndrome. Fortunately, this particular problem is relatively uncommon. Even those in the most severe pain understand the risks of exceeding the safe dosages are too dangerous to justify. Accidental overdose is almost unknown. So the most common problem arises with interactions between tramadol and other drugs with a serotonin content. The most dangerous combinations come with the classes of antidepressants called serotonin-norepinephrine reuptake inhibitors, selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, tricyclic antidepressants, and triptans.

The syndrome can arise even though you take the safe prescribed dose of the painkiller. So the warning is not so much about the painkillers themselves, but to alert people not to self-medicate. Since the rise of the online pharmacy industry, too many people have been buying drugs without a prescription - that means without talking through the risks with a doctor. Obviously, a doctor with access to a person's medical history would immediately identify the dangers and either change the dosages or change the drugs.When people rely on recommendations from friends or the information they glean from the internet to decide what drugs to take, they can be putting themselves at risk.Hopefully,this new warning will prevent problems and keep people safe.
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What is Pain Management?

In a simple case where you have had an accident and,perhaps, broken a bone, there will be acute pain lasting for a reasonably short period of time.Under normal circumstances,these physical injuries heal and the pain goes away.But,sadly,there are many medical conditions where the pain does not go silently into the night. In cases of chronic pain, you and the doctors advising you have to come up with strategies to help you cope - to make the best of your life under difficult circumstances. Now, the medical profession has recognized that, independently of the underlying cause, pain itself is something to be treated. To do so, there are a range of different techniques, including:

  • the use of drugs;
  • different kinds of physical therapy, counseling and psychological support;
  • acupuncture and forms of treatment slightly outside the bounds of conventional Western medicine; and
  • surgery and other forms of procedures to intervene and relieve.
There is a distinction in the type of pain. Some is classified as nociceptive. Here the nervous system is properly identifying the source of the pain as a specific injury or particular point in the body. The symptoms group into radicular and somatic,depending on where the person feels the pain. The pain is said to be neuropathic when the nervous system is not working as it should, i.e. there is no obvious cause for the pain,but the brain insists that there is an injury in a particular place.This type of pain is more difficult to treat because the underlying cause is more difficult to diagnose.

The problem in every case is to decide the best approach. Not everyone reacts to the underlying medical cause in the same way.There are varying degrees of pain and people respond to that pain in slightly different ways. Some are more accepting. Others grow depressed and turn themselves into invalids. So all pain management decisions start with a review of the individual's medical history, asking what has been and can be done to treat the underlying cause,what level of pain intensity the person feels, whether the person has a positive or negative mental attitude, and so on. It is possible that more tests may need to be performed.If targeted surgery or other forms of intervention might relieve the pain, this should be tried first.

While waiting for a specific diagnosis or for the treatments to begin, it is probably appropriate to use one of the standard drugs to control the pain.The best drug is tramadol and it is most commonly prescribed to treat moderate to severe pain across a wide range of cases.You should not self-medicate, i.e. do not go online and buy tramadol without first having a doctor check you out and make sure that it is safe for you to take this drug.You should also not resort to the pill bottle every time you have pain. At an early point,you should have effective treatment either for the underlying cause or for the pain itself and live without using drugs as much or at all.
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Satisfaction Guaranteed

Keep it in your pants? Definitely not. With the new medical inventions that appear every day it is hard to stay ill or feel pain. Only those lazy ones that get up and get to the local pharmacy remain sick.As we all may have heard or seen on TV the problem of impotency has taken over the world.It doesn't mean there is something wrong with men nowadays. It means we have become open with our issues. We are not longer afraid or ashamed to reveal our secrets and share our problems.The problem of erectile dysfunction is not as big as people make it seem. It can be sustained and cared for.

American market is full of pills and medication that promises to turn your troubled existence into a non-problematic life,but no matter how many times we see these commercials and her about this or that product on the radio and in the press - we have to not lose the conscience. It is important to be aware of what we get ourselves into when we chose pills.Every product has good manufacturers behind its back. It costs a lot absolutely a fortune to get the brand name recognized and heard about. It also takes time. Both doctors and patients convince each other that the product they advice or dealt with is the best one on the market. But you have to remember that on this case doctor's opinion is worth much more than our friend's as professionals are there to prescribe us what we need rather than what we want to buy.

One of the most famous erectile dysfunction drugs is Viagra. It always created a fuss around it giving people some controversy. Some say impotency cannot be cured. Other say that the drugs that are meant to help with sexual problems are the plot of our imagination. But the majority keeps insisting that these pills have actually done well to them. At the end of the day, we all find what we are searching for - if you want to believe your medication is going to benefit you, it will - if you don't think it will, well, and the result may not be satisfactory.Erectile dysfunction treatment takes time.We will not try to make you believe that once you start consuming these pills you will never have problems again.The thing is that these drugs give you a temporary effect and it lasts as long as you keep consuming the pill.If you think that you need some sort of medication or if your sexual life is not as good as if was before,please get an advice from a specialist in the local hospital.He will prescribe you the drug you need according to your health issue.

Cialis is known to be a good working drug that gives you less side-effects than the other drugs. It is not as addictive as Viagra and people seem to like it as well.You can buy Cialis online, read some reviews on it on multiple sites,and get some quotes about it.If you have any questions that might interest you,please do not hesitate to ask.Any Cialis web-page will give you feedback on the drug and it will give you a good reason to think about the pill as much as you need to do.This medication has proven to have helped millions of people around the glove,letting them get pleasure from their sexual intercourse.Order Cialis online now and try for yourself. Satisfaction guaranteed.

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What are the Main Psychological Causes of Erectile Dysfunction?

The pharmaceutical industry tries to sell you a basic idea - the idea that everything that goes wrong with you can be cured if you buy the right pill.Unfortunately this has never been, and never will be, true. The human mind is a complicated piece of equipment and, if there is a psychological problem, ordinary pills are useless. In the case of erectile dysfunction (ED), there are a number of different psychological and relationship issues that may have to be resolved before normal sexual activity can be resumed. Yet, the average doctor will concentrate on the biology and ignore the psychology.There are two reasons for this. There are impressive lab tests that justify fee income and can produce black-and-white results in ruling in, or eliminating, diseases and disorders.This can take money while making everyone in the healthcare industry look professionally competent. Secondly, many doctors are embarrassed if they have to start talking to their patients about sex. It burns up time and, unless the doctor has specific expertise, often produces poor outcomes (except, of course, in the size of the bill).

The last thirty years has seen a steady sexual revolution.You see this in a greater acceptance of feminism and the notion of gender equality.The woman's right to choose also shows in the increasing use of oral contraceptives.Before the ED medications came on the market,counselors talked couples through their relationship problems. When the little blue pill appeared, everything when back to biology.Except the drugs do not cure relationship problems. Rightly or wrongly, many men have fixed ideas about how sex is supposed to happen.If something disturbs this, "my way or the highway" approach, this loss of control causes stress and ED appears. Often, the men affected are failing to match up to myths.They are the victims of misinformation.

Put simply, if men are not getting any satisfaction out of sex with their partners, they will avoid situations where sex can occur. The stress will be increased if there is another possible partner, or the men are interested in fetishes but afraid to mention them, or worried about their sexual orientation.A man who has lost interest in sex with his partner, for whatever reason, will find drugs of little help.But, if the underlying relationship is sound, the best of the three ED drugs to take is levitra. It may well be necessary for the couple to go through therapy to resolve their personal issues but, with the support of medication, sexual activity may be restarted. This will require courage because, probably for the first time, the man will have to talk openly about his life, his work, his fears and how he thinks his sex life should run. Hopefully, his partner will be supportive during this time.It is counterproductive to be demanding and expect that, if you buy levitra, everything will be better.Sex is more than producing an erection. It is about your mood and confidence in the relationship.Getting into that mood is the challenge.

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Tomorrow is the Busiest Day of the Week

Wherever you go on the internet,whichever newspapers and magazines you open,there's a familiar marketing message.Apparently,it's easy to lose those unwanted pounds.Yes,of course. The marketers target our insecurities.They show us "before" and "after" pictures and suggest we too can become a person in the right.All we have to do is to buy their product. "Just spend your dollars with us," they wheedle, "and we'll heal your pain." There are a mass of interesting assumptions in all these ads. It seems almost everyone is a target. We all want to shed pounds. That means we must all be unhappy with our current body shape. We must feel uncomfortable, perhaps even the victim of discrimination. Perhaps the health message is getting through and we begin to feel real fear of blocked-up arteries, high blood pressure and heart disease. Whatever the reason, the advertizers scent blood in the water and they are circling round our purses and wallets ready to sink their teeth into our dollars and disappear without delivering on all their promises.

Keeping this real, if it was easy to lose weight, no-one would be overweight.Everyone would have their ideal weight. What makes losing weight so difficult? We just keep putting off action to another day. As the title to this article says, "Tomorrow is the busiest day of the week". Delay makes an easy job harder. But, in the meantime, we buy those weight loss magazines and take a few pills. Hope burns eternal. We are all the victims of one of the not-so-great American myths - that we can get what we want without having to work hard for it. Just look at the tens of thousands who queue up for American Idol and the other shows to discover the next big talent. They all believe success is theirs for the asking.

So let's go back to the drawing-board.The scientific evidence shows we lose the most weight in the shortest time when we combine a calorie-reduced diet with an exercise program. That means eating smaller portions of lean meat and adding fruit,vegetables and a good source of fibre to what we eat. For this to work,there is no tomorrow.You have to live and work through every day, making a commitment and keeping it. But the "keeping" of the commitment is the problem. We often lack the will to keep going. Of course, with money in the bank,we could all hire a personal trainer. This would make us more accountable and focus our minds on the importance of regular activity. But, with the credit crunch and the priority of financial survival, a private trainer is a distant dream. So involve friends and family.Get their support. Invite them to join in. Motivation is reinforced when others are involved.And for those times when you are on your own, there's always phentermine to help you through.This is the best of the appetite suppressants and has been on the maret longer than any other competitor drug.It reduces the hunger pangs and helps you manage your body's messages to eat.With phentermine to keep your body under control, you can focus your mind on losing weight and make it work.You know it makes sense.

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Treat your Xanax addiction

Xanax's generic name is Aprazolam. One of the reasons why Xanax is so popular nowadays is because it happens to be one of the mostly prescribed drugs to cause the addiction around the United States of America.What namely is Xanax then? Xanax is a drug that discourages your brain just like alcohol does. Its impact on one's head is quite similar. Xanax is very famous with teenage abusers who find it easy to get this prescription drug from the backstreet retailer or in their spread on their shelf in the closet.It is to be mentioned that Xanax is not your average safe pain-killer pill. It has its side-effects that all of us should be aware of before we take a dose. Among those are:

  • difficulty concentrating
  • feeling of happiness and depression
  • unusual breathings and rapid beating of the heart
  • feeling tired and bothered sleeping.
  • the loss of memory

It is very important to have the drug prescribed to you by a doctor. He will need to examine you and see the result you are getting from Xanax. It is strictly forbidden to use Xanax with any other medical drugs, especially those who are similar in effects.If you take two of the similar drugs and use them as one - they will interact giving you a side-effect that is going to disappoint you much more than it would help. It is also important to know that no drug is a toy and the ignorant attitude people showed towards such important matters led to death case and terrible overdoses that affected lives.

Side-effect symptoms

Xanax has given multiple people many sleepless nights full of worries and tears.Side-effects are never a joke and being a strong drug Xanax can cause your health some damane you will not want to have in your life.These side-effects will include wetness, shaky hands and easy irritation. Don't you think for a second you can treat yourself from all that without doctors help.You need to advice somebody who is going to make sure you get rid of these effects once and for all.

Xanax Dependence makes Rehab patients?

About the third of a million people checked into the hospital due to the effects Xanax brought them, according to the survey from USA Health Statistic Company.As we previously mentioned Xanax is a very harmous medical pill that should not have any interactions with other drugs.No one should take the drug as a joke.Those who take it without being analyzed first are the ones that suffer the most from various side-effects.It is not easy to work with those who became the casualties of Xanax.Most of those patients have mood changes that influence their behavior.Some of them act like they are constantly in some danger situations.What usually happens is that through different addiction interventions,these addicted people are willing to cope with the fact they are in trouble.What is important here is the awareness of what you go through, the will and believe that it will get better and much spiritual strengths. They have to find a way and trust those people who ate there to help them. With the belief that the addiction is just a matter of time it will all seem so insignificant,temporary and easy.Those people around the addicted ones should be there for them twenty four seven.It should be made clear that Xanax addicts are cared about. It is important that the client is aware of how serious the issue is and mainly that should be the main reason for the treatment.

Xanax is just a drug that requires serious and responsible attitude towards it.We hope everyone knows not to play with drug as at the end of the day the only thing you really play with is your own health.

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Stop suffering from pain in vain!

Pain is what disturbs us from normal existence. Pain killers are the medications people spend most money on due to their effectiveness and hope that the pain will go away.Severe pain is the reason why most of us stop ourselves from living our ordinary life as nothing seems the same when you are unwell.Most medical assistants, who you may address,will tell you that toleration of the pain is not an option.Therefore they will prescribe a good drug to you in order for you to stop suffering. But before we go any further,let's talk about the severe pain relievers in general and discuss their effects on the body.

What is the most important fact that one needs to know about any pain-killer? Well, first of all, it has to be the fact that it is strictly forbidden for those who have allergies especially people allergic to alcoholic drinks and medication in general.Usually when taken out of proportion without previous examination, it is dangerous and risky in its actions.The normal average dose that one can consume without getting into trouble is 300 mg per day.But that,of course, depends on the drug you are about to take.Don't think it is alright to do it with any pill at all. All pain-killers are sold with prescription only.Your doctor will have to examine you good to make sure the drug is right for you.

There are many cases known when individuals consumed drugs that they were not supposed to consume and due to the fact that addiction can bring anxiety,depression and disorders to your life, so think before you go any further with drugs.It is also important to remember that if you happen to be allergic to pain-killing medication or if you have liver disease, kidney problem or mental illness you should avoid the pill. Or if it is the only thing that may help you get rid of your pain - please talk to your specialist in the hospital about the dose.You will probably have to take the reduced dosage. Pregnant women and breastfeeding mothers are not allowed to take any of this medication as it affects the unborn baby in a harmful way.Teenagers under 18 years of age are forbidden to take most of the pain-killers that are meant to treat severe pain

Pain-killers can really work miracles. Tramadol happens to be a good, working drug that can guarantee you a good result. This is a well-known fact. But you have to be careful with it as well as other drugs. Usually pain-relief pills not do always require food as they can go with it as well as without it. Try to not miss any doses and take the pill at the same time everyday. If you are willing to change something in your medical schedule please inform your doctor about it before any problems occur. If it happened so that you missed a dose and your doctor is out of reach, please remember to skip it and take the next one the same time as you took the last one. Don't try to keep up with the drug, rushing into it.It can only do worse. If you have some of the following symptoms after the consumption of any pain relief drugs you have to know you are overdosed. Slow heartbeat, light headed feeling, extreme weakness, fainting or coma are among those that can take your health state to hell. In some, rare cases,overdose can be fatal.

Tramadol is the pain-killing pill that has the appraisals of the most renowned specialists around the world.Nowadays it became very easy to buy the drug in every country just using various online services. Buy Tramadol and say goodbye to pain forever!

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Blood issues are likely to cause ED

It is not big news that erectile dysfunction is not only psychological issue, rising from nervous problems such as depression, anxiety or stress.In fact, most cases of male impotence have different blood problems as the primary cause.Healthy state of blood vessels in your body, and in your penis particularly, is crucial for good and effective functioning of the penis. So when getting to ED treatment,having a drug that has to do with overall blood circulation and the blood flow in the penis is really important. In some cases erectile dysfunction is a side-effect of the drugs you are currently taking for other health conditions such as depression. That's why it is very important to choose the right kinds of medication and to know their side-effects.

Health conditions that are likely to cause ED

One of the most widely seen causes of erectile dysfunction is the damage to blood vessels and nervous tissue delivered by diabetes.Other medical conditions that are likely to cause erectile dysfunction include blood pressure issues,liver or kidney diseases, atherosclerosis, multiple sclerosis, testosterone level issues and damage to blood vessels and nervous tissue during surgeries in the penile area and the spinal chord. Impotence can also be caused by chronic substance abuse such as alcoholism or street drug addiction. Some drugs you are taking currently can also cause erectile dysfunction. These medications include common treatments for depression, chest pain, insomnia, overweight and ulcer. A quick fix of such conditions is likely to improve the degree of impotence but if the condition lasted for a longer period of time it will take a lot more to overcome its effects than simply taking a pill of a drug like Cialis and hope it will solve all of your problems.

Lifestyle strongly affects sexual potency

Do you smoke often? Are you a regular at the local bar? Is your work stressful and you don't get enough sleep on a regular basis? Eliminating all of these factors can significantly improve your sexual health. Men with heavy smoking and drinking habits are more prone to developing ED than non-smokers and non-drinkers. A recent two year study with participation of overweight men who had ED has shown impressive results of lifestyle change on sexual performance.During the course of the study, the participants had to follow a low-calorie diet,exercise on a regular basis, and kick off their nasty habits.As a result,about one third of the test subjects have shown dramatic improvement of the quality of their erections without using such drugs as Cialis at all. So make sure to change your lifestyle towards a healthier one first and maybe it will help you without having to use any additional medications. It all depends on how long you have been experiencing the negative effects of nicotine, alcohol, recreational drugs and unhealthy diet.The rule of thumb here is the longer you follow such a lifestyle, the harder it will be to get back to the normal and healthy one and get significant improvements. Still, it's all possible so make sure to take that change towards a better and healthier way of living your life.

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Are men and women the same when it comes to pain?

In these more modern times of sexual equality, it may not be politically correct to talk about differences between men and women.Unfortunately,the medical profession cannot ignore the increasing volume of scientific evidence that there are important differences, particularly when it comes to pain management.In this,it is important to distinguish between biological sex and gender.There are visual tests for the presence or absence of reproductive organs, and lab tests for chromosomes that help to say whether this is a man or woman.Gender,on the other hand, is a list of the social roles society defines for people.This can be complicated when people choose to act or behave in ways considered more appropriate for the opposite sex.As an example of the problem, you only have to look at the complaints that Caster Semenya is not a woman. How can this muscular person from South Africa suddenly beat the word record for the 800m by one second and be a woman?

The last decade has seen a rapid rise in the volume of research into gender differences in the response to pain.There is clear evidence that women are more likely to consult a doctor about pain and to take drugs to relieve that pain.As a result,the national statistics show more women than men suffering from the more common medical conditions causing pain such as arthritis,irritable bowel syndrome,fibromyalgia, etc.In tests involving healthy volunteers,women are more likely to report higher levels of pain than men.This applies regardless of the other factors of age,race,ethnicity and religion.Interestingly,brain scans have shown that pain affects different parts of the brain. In women, the limbic area which also affects emotions is stimulated more than in men.

The speculation is that the differences in brain activity flow from early human development. Men were the stronger group with responsibility to fight to defend the community. This means being prepared to accept pain.Women were expected to respond to danger by nurturing and protecting the young,running away if necessary.Today,men remain less willing to admit to feeling pain and are reluctant to seek medical help. It does not matter whether this is a biological or gender difference,the statistical evidence for this unwillingness to seek help is absolutely clear.But,equally clear is that tramadol relieves the pain of both a macho man and an emotional woman. Even though there may be gender differences,the biological effect of tramadol is the same on a human body.It relieves moderate to severe pain.So,perhaps it is time for all men suffering in silence to overcome the cultural conditioning that threatens their self-esteem if they admit to pain. Once you have clearance from your local healthcare provider that there are no problems in you taking this drug, go online and buy tramadol from the privacy of your own home. This relieves the pain and preserves your image.

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3 Non-Small Cell Lung Cancer Treatments Explained

There are two main types of cancer,non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).Of the two,the lung is much more prevalent,representing 80% of cases.It begins when cells enter the lungs expand and multiply rapidly and uncontrollably.Over time this can lead to malignant neoplasms (cancer),development of tumor in the lungs,which then kills some cells, as grows.Although this condition can be fatal there are several treatments that can be used depending on how advanced the cancer has become.This article will discuss three of these treatments for NSCLC.

1) SURGERY - Surgery is usually used to treat cancer that has spread beyond the lungs.There are two main types of operations that are used to treat non-small cell lung cancer.Where can be in one of the lobes of the lung removed in a surgical procedure called lobectomy.However,if the cancer has spread beyond the entire lung lobe may then be disposed of in a procedure called pneumonectomy.

2) chemotherapy - chemotherapy,which involves the use of drugs kill cancer cells for the treatment of lung.This is often used when the cancer became more advanced and surgery is no longer feasible option.However,can also be used prior to surgery (for cancer cell shrinkage,and make the process easier to perform) or after surgery (to kill off any remaining cancer cells and reduce the risk of recurrence).Unfortunately,chemotherapy treatment is complete and has numerous unpleasant related side effects,including feelings of illness,poor appetite and hair loss. However,in most cases,these symptoms disappear when the chemotherapy ends.

3) Radiotherapy - Radiotherapy means the use of high doses of radiation to destroy cancer cells.It may be internal (if the radioactive implants placed in the malignant cells) or external (if the radioactive rays are aimed at non-cancerous tumor of the body).Like chemotherapy,this type of non-small cell lung cancer is normally used when the cancer has spread beyond the lungs and the operation is not possible.However,it can also be used before and after surgery to make it easier to implement,and minimize the possibility of NSCLC returned.

Cancer is a terrible disease and learning, you have developed non-small cell lung cancer can be very unpleasant.However,remember that it can be seen especially if detected early stages.I hope this article gave a review of treatment options,lung,but to get the whole image you should go see your doctor.They will be able to provide you with expert advice and give you the most appropriate treatment.While there has been any intention to make this article accurate and informative,it is intended for general information only.Lung cancer is very serious, life-threatening situation,and you should discuss any concerns,treatments or lifestyle changes fully with your doctor.
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